Motohiro Sekiya Selected Research

Lipodystrophy

1/2018

Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance.

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Motohiro Sekiya Research Topics

Disease

14	Atherosclerosis 03/2019 - 08/2002
13	Obesity 10/2023 - 12/2003
8	Insulin Resistance 03/2020 - 12/2003
7	Type 2 Diabetes Mellitus (MODY) 01/2024 - 12/2015
4	Hyperglycemia 10/2022 - 12/2003
4	Inflammation (Inflammations) 03/2020 - 01/2017
4	Hyperlipidemias (Hyperlipidemia) 07/2018 - 01/2016
4	Hypertriglyceridemia 01/2018 - 08/2011
3	Non-alcoholic Fatty Liver Disease 12/2022 - 07/2017
2	Starvation 01/2021 - 11/2007
2	Body Weight (Weight, Body) 01/2019 - 07/2018
2	Hypercholesterolemia 11/2016 - 09/2006
2	Fatty Liver 12/2015 - 05/2004
2	Neoplasms (Cancer) 06/2005 - 07/2003
1	Corneal Opacity 03/2024
1	Peripheral Nervous System Diseases (PNS Diseases) 03/2024
1	Tangier Disease 03/2024
1	Glioblastoma (Glioblastoma Multiforme) 01/2023
1	Carcinogenesis 01/2023
1	Mitochondrial Diseases (Mitochondrial Disease) 12/2022
1	Genetic Predisposition to Disease (Genetic Predisposition) 12/2022
1	Hepatitis 12/2022
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2022
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 10/2022
1	Dementia (Dementias) 09/2022
1	Aniridia 08/2022
1	Muscle Weakness 01/2022
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022
1	Cognitive Dysfunction 01/2021
1	Hyperuricemia 01/2020
1	Albuminuria 07/2018
1	Diabetic Nephropathies (Diabetic Nephropathy) 07/2018
1	Dyslipidemias (Dyslipidemia) 07/2018
1	Hypoxia (Hypoxemia) 04/2018
1	Lipodystrophy 01/2018
1	Fibrosis (Cirrhosis) 01/2018
1	Weight Loss (Weight Reduction) 11/2017

Drug/Important Bio-Agent (IBA)

9	CholesterolIBA 03/2019 - 08/2002
6	LipidsIBA 10/2023 - 11/2008
6	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 12/2015
6	Cholesterol Esters (Cholesteryl Esters)IBA 10/2014 - 08/2002
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 10/2007
5	Sterol Regulatory Element Binding Protein 1IBA 12/2022 - 06/2005
5	Insulin (Novolin)FDA Link 09/2022 - 09/2009
5	Sterol Esterase (Hormone-Sensitive Lipase)IBA 01/2011 - 08/2002
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 12/2015
4	Messenger RNA (mRNA)IBA 01/2023 - 06/2005
4	Transcription Factors (Transcription Factor)IBA 01/2021 - 07/2003
4	Triglycerides (Triacylglycerol)IBA 07/2018 - 06/2005
4	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 07/2018 - 04/2017
4	EnzymesIBA 01/2016 - 06/2005
3	Blood Glucose (Blood Sugar)IBA 10/2022 - 12/2015
3	Fatty Acid ElongasesIBA 01/2020 - 10/2007
3	oxidized low density lipoproteinIBA 07/2018 - 09/2006
3	LDL Receptors (LDL Receptor)IBA 04/2017 - 08/2011
2	PPAR alphaIBA 01/2023 - 12/2003
2	Sodium-Glucose Transporter 2 InhibitorsIBA 12/2022 - 11/2017
2	fibroblast growth factor 21IBA 03/2020 - 07/2018
2	Sucrose (Saccharose)IBA 03/2020 - 01/2020
2	Farnesyl-Diphosphate Farnesyltransferase (Squalene Synthase)IBA 05/2015 - 09/2006
2	SterolsIBA 08/2011 - 05/2004
2	Lipoproteins (Lipoprotein)IBA 08/2011 - 07/2004
2	ElementsIBA 08/2011 - 05/2004
2	LeptinIBA 09/2009 - 12/2003
1	HDL LipoproteinsIBA 03/2024
1	Nonsense Codon (Nonsense Mutation)IBA 03/2024
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 03/2024
1	RNA (Ribonucleic Acid)IBA 01/2024
1	C-terminal binding proteinIBA 10/2023
1	Malonyl Coenzyme A (Malonyl CoA)IBA 01/2023
1	MicroRNAs (MicroRNA)IBA 01/2023
1	Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)IBA 01/2023
1	Methionine (L-Methionine)FDA Link 12/2022
1	Choline (Choline Chloride)IBA 12/2022
1	AntibodiesIBA 10/2022
1	Asparaginase (Elspar)FDA Link 10/2022
1	KynurenineIBA 09/2022
1	Branched-Chain Amino AcidsIBA 09/2022
1	Tryptophan (L-Tryptophan)FDA Link 09/2022
1	Hemoglobins (Hemoglobin)IBA 08/2022
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Phospholipases (Phospholipase)IBA 01/2020
1	CeramidesIBA 01/2020
1	Uric Acid (Urate)IBA 01/2020
1	1-octacosanol (octacosanol)IBA 01/2019
1	policosanolIBA 01/2019
1	(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA 07/2018
1	Fenofibrate (CiL)FDA LinkGeneric 07/2018
1	Malondialdehyde (Propanedial)IBA 07/2018
1	LDL CholesterolIBA 07/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2018
1	LigandsIBA 01/2018
1	PhosphoenolpyruvateIBA 01/2018
1	Genetic Markers (Genetic Marker)IBA 01/2018
1	Sodium-Glucose Transport ProteinsIBA 11/2017
1	Oleic Acid (Oleate)IBA 01/2017
1	PalmitatesIBA 01/2017

Therapy/Procedure

1	Tonsillectomy 03/2024
1	Glycemic Control 09/2022
1	Cardiopulmonary Resuscitation (CPR) 01/2022